Started by taxed, May 13, 2021, 01:25:30 PM
QuoteSuperparamagnetic nanoparticle delivery of DNA vaccineAbstractThe efficiency of delivery of DNA vaccines is often relatively low compared to protein vaccines. The use of superparamagnetic iron oxide nanoparticles (SPIONs) to deliver genes via magnetofection shows promise in improving the efficiency of gene delivery both in vitro and in vivo. In particular, the duration for gene transfection especially for in vitro application can be significantly reduced by magnetofection compared to the time required to achieve high gene transfection with standard protocols. SPIONs that have been rendered stable in physiological conditions can be used as both therapeutic and diagnostic agents due to their unique magnetic characteristics. Valuable features of iron oxide nanoparticles in bioapplications include a tight control over their size distribution, magnetic properties of these particles, and the ability to carry particular biomolecules to specific targets. The internalization and half-life of the particles within the body depend upon the method of synthesis. Numerous synthesis methods have been used to produce magnetic nanoparticles for bioapplications with different sizes and surface charges. The most common method for synthesizing nanometer-sized magnetite Fe3O4 particles in solution is by chemical coprecipitation of iron salts. The coprecipitation method is an effective technique for preparing a stable aqueous dispersions of iron oxide nanoparticles. We describe the production of Fe3O4-based SPIONs with high magnetization values (70 emu/g) under 15 kOe of the applied magnetic field at room temperature, with 0.01 emu/g remanence via a coprecipitation method in the presence of trisodium citrate as a stabilizer. Naked SPIONs often lack sufficient stability, hydrophilicity, and the capacity to be functionalized. In order to overcome these limitations, polycationic polymer was anchored on the surface of freshly prepared SPIONs by a direct electrostatic attraction between the negatively charged SPIONs (due to the presence of carboxylic groups) and the positively charged polymer. Polyethylenimine was chosen to modify the surface of SPIONs to assist the delivery of plasmid DNA into mammalian cells due to the polymer's extensive buffering capacity through the "proton sponge" effect.
Quote from: Hoofer on May 14, 2021, 07:20:01 AMLast night, wifey & I watched a couple of videos of that - some were 2 days AFTER the Jab, magnet was still sticking. It set off this guy's metal detector..I keep asking, this this metallic substance just flow around forever in your body, or settles in some organ, or do you "sweat it out", "Piss it out", "Exhale it" or "crap it out"?IF it's with you "forever" - like some kind of "Genetic Receptical" waiting & ready for some Virus/Genetic code to "plug into it" - we're in big trouble!Someone (like a Fauchi) decides you've lived long enough, so you get a "Booster" ... 3 years, you're dead, and nobody associates it with that "Booster" you got, but, it had exactly what was needed to slowly shut down an organ or two. This stuff creeps me out.
Quote from: Solar on May 14, 2021, 07:21:12 AMCan you say, "You've Been Chipped"?
Quote from: Hoofer on May 14, 2021, 07:58:57 AMYeah, Wifey was asking if I had something that could "read a nano chip" - if they inserted one. nope.I'd be inclined to use a powerful magnet & vacuum pump to SUCK that crap out. It'd make one heck of a sore spot for a few days ... but, injecting some kind of nano-metallic substance into me ... hell no!
Quote from: rp5x5 on May 15, 2021, 07:53:23 PMSaying, "super paramagnetic iron oxide nanoparticles"Might make you sound precocious (SPIONs_-Spy-ons)
Quote from: Stu Gatze on May 15, 2021, 11:21:25 PMWhy is it that almost everything the modern progressive little liberal endorses, .. there is always generally something dirty or corrupted with it?
Quote from: Sauce on May 15, 2021, 11:29:08 PMTBecause they are Evil and/or Satanic OR are being manipulated by people who are because they themselves are gullible (but ambitious) sheeple....the latter being destined for middle management in the 7 levels of hell.